Immune Modelation

Immune Modelation

Immune modulation studied by means of vaccination responses:
To study immune modulatory capacities of compounds, CURAX offers animal tests as recommended by the World Health Organisation (WHO) and International Institute of Life Sciences (ILSI). These tests provide you with a fast answer on the effect of your compound on the immune system by using the immune response against a certain vaccine. All vaccines used are normally approved for medical purposes, ensuring full compatibility any future clinical studies you would like to perform. According to our general policy the protocol can be adjusted to your own wishes.

Outcome:
Vaccine specific and non-specific ex vivo cellular responses Cytokines & other mediators Vaccine specific antibody titres Delayed type hypersensitivity

Literature:
1) Vos et al. A specific prebiotic oligosaccharide mixture stimulates delayed-type hypersensitivity in a murine influenza vaccination model. Int J  Immunopharmacol. 2006, 6(8), 1277-86.

2) Albers et al. Markers to measure immunomodulation in human nutrition intervention studies, British Journal of Nutrition 2005, 94, 452–481, ILSI 2005